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DNA GLYCOSYLASES
Descriptors Found:
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DeCS
Descriptor
English
:
DNA Glycosylases
Descriptor
Spanish
:
ADN Glicosilasas
Descriptor
Portuguese
:
DNA Glicosilases
Synonyms
English
:
DNA N-glycosidase
Tree Number:
D08.811.074.249
D08.811.277.450.430.099
Definition
English
:
A
family
of
DNA repair enzymes
that recognize damaged nucleotide bases and remove them by hydrolyzing the N-glycosidic bond that attaches them to the
sugar
backbone of the
DNA
molecule. The process called BASE EXCISION REPAIR can be completed by a
DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE
which excises the remaining
RIBOSE
sugar
from the
DNA.
History Note
English
:
2004; use DNA GLYCOSIDASES (NM) 1980-2003
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
38126
Unique Identifier:
D045647
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS